研究業績

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Development of anti-HB-EGF immunoliposomes for the treatment of breast cancer.

【Author】

Nishikawa K, Asai T, Shigematsu H, Shimizu K, Kato H, Asano Y, Takashima S, Mekada E, Oku N, Minamino T.

【Journal】

J Control Release. 160(2),274-80.

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2012.07.10

Deficiency of type 1 cannabinoid receptors worsens acute heart failure induced by pressure overload in mice.

【Author】

Liao Y, Bin J, Asakura M, Xuan W, Chen B, Huang Q, Xu D, Ledent C, Takashima S, Kitakaze M.

【Journal】

Eur Heart J. 33(24),3124-33.

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2012.12.01

H(2) Mediates Cardioprotection Via Involvements of K(ATP) Channels and Permeability Transition Pores of Mitochondria in Dogs.

【Author】

Yoshida A, Asanuma H, Sasaki H, Sanada S, Yamazaki S, Asano Y, Shinozaki Y, Mori H, Shimouchi A, Sano M, Asakura M, Minamino T, Takashima S, Sugimachi M, Mochizuki N, Kitakaze M.

【Journal】

Cardiovasc Drugs Ther. 26(3),217-26.

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2012.06.01

Identification of RNF213 as a susceptibility gene for moyamoya disease and its possible role in vascular development.

【Author】

Liu W, Morito D, Takashima S, Mineharu Y, Kobayashi H, Hitomi T, Hashikata H, Matsuura N, Yamazaki S, Toyoda A, Kikuta K, Takagi Y, Harada KH, Fujiyama A, Herzig R, Krischek B, Zou L, Kim JE,

【Journal】

PLoS ONE. 6(7), e22542.

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2011.11.01

AMP-activated protein kinase enhances the phagocytic ability of macrophages and neutrophils.

【Author】

Bae HB, Zmijewski JW, Deshane JS, Tadie JM, Chaplin DD, Takashima S, Abraham E.

【Journal】

FASEB J. 25(12) 4358-68.

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2011.12.01

ATF6b is a host cellular target of the Toxoplasma gondii virulence factor ROP18.

【Author】

Yamamoto M, Ma JS, Mueller C, Kamiyama N, Saiga H, Kubo E, Kimura T, Okamoto T, Okuyama M, Kayama H, Nagamune K, Takashima S, Matsuura Y, Soldati-Favre D, Takeda K.

【Journal】

J Exp Med. 208(7),1533-46.

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2011.07.04

Isoform-specific intermolecular disulfide bond formation of heterochromatin protein 1 (HP1).

【Author】

Higo S, Asano Y, Kato H, Yamazaki S, Nakano A, Tsukamoto O, Seguchi O, Asai M, Asakura M, Asanuma H, Sanada S, Minamino T, Komuro I, Kitakaze M, Takashima S

【Journal】

J Biol Chem 285(41),31337-47.

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2010.10.08

Ablation of C/EBP homologous protein attenuates endoplasmic reticulum-mediated apoptosis and cardiac dysfunction induced by pressure overload.

【Author】

Fu HY, Okada K, Liao Y, Tsukamoto O, Isomura T, Asai M, Sawada T, Okuda K, Asano Y, Sanada S, Asanuma H, Asakura M, Takashima S, Komuro I, Kitakaze M, Minamino T.

【Journal】

Circulation, 122(4),361-9.

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2010.07.27

Anti-human HB-EGF monoclonal antibodies inhibiting ectodomain shedding of HB-EGF and Diphtheria Toxin binding.

【Author】

Hamaoka, M., Chinen, I., Murata, T., Takashima, S., Iwamoto, R.,Mekada, E.,

【Journal】

J Biochem. 148(1),55-69.

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2010.07.01

X-box binding protein 1 regulates brain natriureticpeptide through a novel AP1/CRE-like element in cardiomyocytes.

【Author】

Sawada T, Minamino T, Fu HY, Asai M, Okuda K, Isomura T, Yamazaki S, Asano Y, Okada KI, Tsukamoto O, Sanada S, Asanuma H, Asakura M, Takashima S, Kitakaze M, Komuro I.

【Journal】

J Mol Cell Cardiol. 48(6),1280-128

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2010.07.01